Yakin Byoto Online -New Operation-, officially titled 『夜勤病棟オンライン -New Operation-』 in Japanese, has been announced as a new game for FANZA GAMES, with pre-registration now open across its browser and Android versions.
The adults-only title brings characters from multiple previous entries into a card-battle RPG structure. Players collect cards, build decks, explore the hospital and clear full-auto battles to progress through character stories.
> Adult content notice: the game and its official website are restricted to users aged 18 or older. This article covers its announcement, gameplay systems, characters and release information without explicit material.
Quick Summary
- Official Japanese title: 夜勤病棟オンライン -New Operation-
- Romanization: Yakin Byoto Online -New Operation-
- Format: online game
- Age category: 18+
- Genre: card battle RPG
- Status: pre-registration open
- Announcement date: October 15, 2026
- Release date: unannounced
- Price: free to play
- Monetization: in-game purchases
- Platform: PC browser
- Platform: smartphone browser
- Platform: GAMES STORE
- GAMES STORE version: Android
- Steam version: unannounced
- Console versions: unannounced
- Listed provider: NeuralPicks
- Distribution: FANZA GAMES
- Official PV: available through the official website
- Primary setting: St. Lupinus General Hospital / 聖ルピナス総合病院
- Player role: a doctor who once worked under Ryuji Hirasaka
- Returning figure: Ryuji Hirasaka
- Core gameplay: collecting cards
- Core gameplay: building decks
- Core gameplay: hospital exploration
- Battle system: full-auto card battle
- Progression: victories advance character stories
- Announced character: Ren Nanase
- Announced character: Ako Fujisawa
- Announced character: Narumi Jinguji
- Announced character: Sayuki Tezuka
- Announced character: Yu Yagami
- Announced character: Hiyori Kisaragi
- Announced character: Koko Amamiya
- Ren Nanase origin: Yakin Byoto
- Ako Fujisawa origin: Yakin Byoto
- Narumi Jinguji origin: Yakin Byoto
- Sayuki Tezuka origin: Yakin Byoto II
- Yu Yagami origin: Yakin Byoto III
- Hiyori Kisaragi origin: Yakin Byoto III
- Koko Amamiya origin: Yakin Byoto Zero
- Ren Nanase voice: Kaname Shiratsuki
- Ako Fujisawa voice: Nagomi Naruse
- Narumi Jinguji voice: Mashiro Kazahana
- Sayuki Tezuka voice: Nanae Hoshimi
- Yu Yagami voice: Aika Kashiwagi
- Hiyori Kisaragi voice: Kurumi
- Koko Amamiya voice: Inemuri Suyako
- Pre-registration: includes signup milestones
- 5,000 signup reward: 200 Yasho-seki / 夜晶石
- 10,000: 300 Yasho-seki
- 30,000: 1,000 Yasho-seki
- 50,000: 1,500 Yasho-seki
- 70,000: 2,000 Yasho-seki
- Pre-registration gacha: available
- Global gacha milestone: up to 8 million spins
- Global rewards: Yasho-seki, SSR level medicine and gacha tickets
- Personal spin milestones: 5 through 350 spins
- 350 personal spins: SSR guaranteed gacha ticket
- DMM Point lottery tickets: available through personal milestones
- DMM Point campaign: more than 4,000 winners
- Top prize: 100,000 DMM Points
- Total prize pool: 1 million DMM Points
- Current status: awaiting a launch-date announcement
PV, Key Visual and Gameplay System

The Series Returns as a Card Battle RPG
The game places players in the role of a doctor with a past connection to Ryuji Hirasaka. Years later, the protagonist arrives at St. Lupinus General Hospital and becomes involved with Hirasaka once again.
Gameplay is built around card collection. The official website shows players choosing characters, exploring the hospital, creating decks and entering full-auto battles.
Characters From Multiple Entries Come Together
One of New Operation's main features is its crossover roster drawn from different parts of the series.
The initial lineup includes Ren Nanase, Ako Fujisawa and Narumi Jinguji from Yakin Byoto, Sayuki Tezuka from Yakin Byoto II, Yu Yagami and Hiyori Kisaragi from Yakin Byoto III, and Koko Amamiya from Yakin Byoto Zero.
The official website presents the project around returning characters from across the franchise, leaving room for the roster to expand before launch.
Pre-Registration Includes Multiple Reward Tracks
Signup milestones award Yasho-seki, with the currently displayed registration tiers reaching 70,000 users.
A separate pre-registration gacha offers rewards based on both total community spins and individual spin counts. Certain personal milestones also grant DMM Point lottery tickets, with a combined 1 million DMM Points being distributed across more than 4,000 winners.
The Release Date Remains Unannounced
Pre-registration is already available for the PC browser, smartphone browser and Android GAMES STORE versions.
An exact launch date has not yet been provided. The final launch roster, card lineup and post-release service plans also remain undisclosed.
Why This Matters
1) The series is being rebuilt around a live-service card RPG structure
The new gameplay loop combines card collection, deck building, hospital exploration and automatic battles.
2) The roster spans several previous entries
Characters from Yakin Byoto, II, III and Zero are already part of the initial reveal.
3) The pre-registration campaign is extensive
In addition to in-game currency and gacha tickets, the campaign includes a 1 million DMM Point prize pool.
Yakin Byoto Online -New Operation- Information
For now, the additional important information currently known includes:
- the official Japanese title is 『夜勤病棟オンライン -New Operation-』
- the romanization used in this article is Yakin Byoto Online -New Operation-
- the game is restricted to users aged 18 and older
- the official website uses an age gate
- distribution is tied to the FANZA GAMES ecosystem
- NeuralPicks is listed as the provider
- the game follows a free-to-play model
- in-game purchases are supported
- the PC version runs in a browser
- the smartphone version also runs in a browser
- the Android version will be distributed through GAMES STORE
- a native iOS version has not been announced
- Steam has not been announced
- PlayStation has not been announced
- Xbox has not been announced
- Nintendo Switch has not been announced
- the release date remains unannounced
- pre-registration is currently open
- an official PV is available through the website
- gameplay revolves around cards
- players obtain cards through the game's systems
- cards are combined into decks
- players can select a character to focus on
- exploration takes place inside the hospital
- battles use the player's prepared deck
- battles run in full-auto format
- winning battles advances story content
- gameplay images on the website come from a development build
- the official site warns that visuals may change before release
- the protagonist works at St. Lupinus General Hospital
- Ryuji Hirasaka is a key figure in the premise
- Ren Nanase is among the revealed characters
- Ren Nanase is voiced by Kaname Shiratsuki
- Ako Fujisawa is among the revealed characters
- Ako Fujisawa is voiced by Nagomi Naruse
- Narumi Jinguji is among the revealed characters
- Narumi Jinguji is voiced by Mashiro Kazahana
- Sayuki Tezuka is among the revealed characters
- Sayuki Tezuka is voiced by Nanae Hoshimi
- Yu Yagami is among the revealed characters
- Yu Yagami is voiced by Aika Kashiwagi
- Hiyori Kisaragi is among the revealed characters
- Hiyori Kisaragi is voiced by Kurumi
- Koko Amamiya is among the revealed characters
- Koko Amamiya is voiced by Inemuri Suyako
- signup milestones begin at 5,000 users
- signup rewards use Yasho-seki
- the highest currently displayed signup tier is 70,000
- the pre-registration gacha has community-wide spin milestones
- the highest displayed global milestone reaches 8 million spins
- gacha tickets are included among global rewards
- SSR level medicine is also included
- personal milestones begin at five spins
- the highest displayed personal milestone is 350 spins
- an SSR guaranteed gacha ticket is awarded at 350 spins
- DMM Point lottery tickets are also available
- the top lottery prize is 100,000 DMM Points
- two 100,000-point prizes are available
- 20 prizes are worth 10,000 points
- 200 prizes are worth 1,000 points
- 4,000 prizes are worth 100 points
- the total campaign prize pool is 1 million DMM Points
- more than 4,000 players can receive DMM Point prizes
- further launch details remain unannounced
- official information is available through the Official Website
- updates are available through Official X
- the pre-registration announcement is available through the Exact Official X Post
Closing
Yakin Byoto Online -New Operation- brings characters from several entries into a card-battle RPG built around deck construction, exploration and full-auto combat.
Pre-registration is live for its browser and Android versions, while the exact launch date remains unannounced. Additional characters, cards and service details are still expected later.